Sanad, H., Mohamed, A., Abd-elraouf, A. (2019). Comparative study between three Different Doses of Magnesium Sulfate as a Technique of Hypotensive Anesthesia during Functional Endoscopic Sinus Surgery. The Egyptian Journal of Hospital Medicine, 74(8), 1759-1768. doi: 10.21608/ejhm.2019.28676
Hamed A. Sanad; Amgad Z. Mohamed; Ahmed A. Abd-elraouf. "Comparative study between three Different Doses of Magnesium Sulfate as a Technique of Hypotensive Anesthesia during Functional Endoscopic Sinus Surgery". The Egyptian Journal of Hospital Medicine, 74, 8, 2019, 1759-1768. doi: 10.21608/ejhm.2019.28676
Sanad, H., Mohamed, A., Abd-elraouf, A. (2019). 'Comparative study between three Different Doses of Magnesium Sulfate as a Technique of Hypotensive Anesthesia during Functional Endoscopic Sinus Surgery', The Egyptian Journal of Hospital Medicine, 74(8), pp. 1759-1768. doi: 10.21608/ejhm.2019.28676
Sanad, H., Mohamed, A., Abd-elraouf, A. Comparative study between three Different Doses of Magnesium Sulfate as a Technique of Hypotensive Anesthesia during Functional Endoscopic Sinus Surgery. The Egyptian Journal of Hospital Medicine, 2019; 74(8): 1759-1768. doi: 10.21608/ejhm.2019.28676
Comparative study between three Different Doses of Magnesium Sulfate as a Technique of Hypotensive Anesthesia during Functional Endoscopic Sinus Surgery
Department of Anesthesia and Intensive Care, Faculty of Medicine, Al-Azhar University
Abstract
Background: Hypotensive anesthesia represents a great challenge for the anesthetists. Although, there is great benefit from inducing hypotensive anesthesia, there is a great risk of major morbidity and mortality. Aim of this work: Evaluation of the optimal dose of MgSo4 to create hypotension during functional endoscopic sinus surgery. Materials and methods: This prospective, control, randomized, clinical study was conducted on 60 patient divided into three groups. Patients were recruited from the Department of Anesthesia and Intensive Care, AL- Azhar University Hospitals. Each group received different dose of MgSo4 5-10-15 mg/kg/h. Then, we took measures of Bp, Spo2, HR and cortisol. Our observations then were statically analyzed. Results: There was more stability in hemodynamic parameter in group II and III. There was significant decrease in blood pressure in group III. In addition, there was a decrease in heart rate in group II and III but this decrease wasn't significant. Magnesium sulphate decreased release of stress hormone especially in group III. Conclusion: Deliberated hypotension is very useful during surgery to decrease time and blood loss. Magnesium sulphate is one of the most useful techniques to induce hypotension during surgical operation. We suggest that using magnesium sulphate in 40 mg\kg as loading dose then continuous infusion at 15 mg\kg\h is the most effective and safest technique. Magnesium sulphate is very useful agent to abolish stress response.
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