Evaluation of Doppler Study of Uterine Artery and Subendometrial Blood Flow in Unexplained Recurrent Pregnancy Loss

Elhessy, Ahmed Mohamed; Shalaby, Hend Abdelrhman; Zayed, Abdelhady Abdelhady; El-Zayadi, Ahmed Abdelhamid

doi:10.21608/ejhm.2023.282143

Evaluation of Doppler Study of Uterine Artery and Subendometrial Blood Flow in Unexplained Recurrent Pregnancy Loss

Document Type : Original Article

Authors

10.21608/ejhm.2023.282143

Abstract

Background: Abortion is considered recurrent when it happens spontaneously and successively at least two times. Recurrent pregnancy loss (RPL) can occur due to maternal or fetal factors. Studies recommend that uterine artery perfusion could control endometrial receptivity, and that poor uterine perfusion may be a main cause of unexplained abortion. Objective: The aim of the current study is to investigate the ability of uterine Doppler in assessing uterine causes of RPL.
Patients and methods: A case-control study was carried out on females attended to Fetal Medicine Care Unit at Mansoura University Hospital and Damietta General Hospital, from November 2019 to November 2020. The study included 160 of non-pregnant women, who were divided into 2 groups; Group A included 80 participants presented with a history of idiopathic recurrent pregnancy loss (RPL group), and Group B included 80 participants who had no history of abortion and had at least one child born at term (Control group).
Results: There was statistically significant higher mean mid luteal endometrial thickness detected in case group than in control group (P<0.001). The subendometrial blood flow resistance index was increased in RPL (P<0.001). Significant increases in right and left uterine artery pulsatility index (PI) and resistance index (RI) were recorded in RPL cases in comparison with the control group (P<0.001).
Conclusion: Uterine Doppler is a simple available method that can help in evaluation of RPL, especially PI and RI that were significantly increased in women with RPL.

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