Prevalence of Antibiotic Resistance in Pediatric Malignancy Patients: A Two-Year Retrospective Study in Basra City

Abdul Jabbar, Hanan AlAulddin; Hadi, Ali Mohammed

doi:10.21608/ejhm.2023.281264

Prevalence of Antibiotic Resistance in Pediatric Malignancy Patients: A Two-Year Retrospective Study in Basra City

Document Type : Original Article

Authors

10.21608/ejhm.2023.281264

Abstract

Background: The most frequent side effects of chemotherapy are infections, which have substantial morbidity and mortality rates in immunocompromised patients.
Aim: Toscreen the prevalence of resistance between antibiotics administered to infected patients in hematological malignancy wards.
Subjects and Methods: A retrospective cross-sectional study of pediatric oncology patients was conducted from January 2021 to June 2022 at Basra children hospital. The study included 500 patients with hematological malignancies.
Results: This study involved 57.8% male and 42.2% female patients. Leukemia was the most common diagnosis 59% while other solid tumors was 41%. Febrile neutropenia was only 5.8%, bacterial infection was predominant at 49.8% while the fungal infection was 9.4%, and 4.8% suspected viral infection. We found that the high percentage of antibiotics used were Cephalosporin (41.4%) and the lower percentage of antibiotics were Quinolone 0.4%.
Conclusion: The most frequent form of infection was a bacterial infection, and the most frequently prescribed antibiotic for oncology patients was cephalosporin. The chest represented the most severely infected place.

Keywords