Abdel-Kader, M., Hasan, A., Mohammed, M., Alsagheer, G. (2023). Outcome of On-Demand Tadalafil in Premature Ejaculation. The Egyptian Journal of Hospital Medicine, 90(1), 754-756. doi: 10.21608/ejhm.2023.279926
Mohammad Sayed Abdel-Kader; Ahmed Mahmoud Hasan; Mahmoud Mohsen Mohammed; Gamal A. Alsagheer. "Outcome of On-Demand Tadalafil in Premature Ejaculation". The Egyptian Journal of Hospital Medicine, 90, 1, 2023, 754-756. doi: 10.21608/ejhm.2023.279926
Abdel-Kader, M., Hasan, A., Mohammed, M., Alsagheer, G. (2023). 'Outcome of On-Demand Tadalafil in Premature Ejaculation', The Egyptian Journal of Hospital Medicine, 90(1), pp. 754-756. doi: 10.21608/ejhm.2023.279926
Abdel-Kader, M., Hasan, A., Mohammed, M., Alsagheer, G. Outcome of On-Demand Tadalafil in Premature Ejaculation. The Egyptian Journal of Hospital Medicine, 2023; 90(1): 754-756. doi: 10.21608/ejhm.2023.279926
Outcome of On-Demand Tadalafil in Premature Ejaculation
Background: One of the most prevalent sexual diseases among men is premature ejaculation (PE). Phosphodiesterase type-5 (PDE5) inhibitors used on-demand were successful in treating PE, according to several studies. Aims: To evaluate the safety and the efficacy of tadalafil in treatment of patients with premature ejaculation. Patients and methods: This study was conducted on 30 patients with at least a 3-month history of PE. All patients were submitted to clinical examination with stress on genital examination, laboratory testing for complete blood picture, and hormonal profile. Patients were received on-demand 20 mg tadalafil 2 hours before intercourse. Intravaginal ejaculatory latency time (IELT) was measured in all patients before and after the treatment (at 4, 8, and 12 weeks). Results: The mean age was 33.03 ± 7.5 years, with mean body mass index (BMI) of 28.8 ± 2.9 kg/m². The baseline IELT score was 39.4 ± 10. There was highly statistically significant (p-value < 0.001) increased 4 weeks IELT score (186.6 ± 24.4), 8 weeks IELT score (188.5 ± 21) and 12 weeks IELT score (187.2 ± 20.5) when compared with baseline IELT score (39.4 ± 10). Conclusion: Tadalafil 20 mg on demand is thought to help PE patients with good levels of safety and tolerability.