Renal Status of Inflammatory Bowel Disease Patients in Assiut University Hospital: Single Center Study

Background: Idiopathic inflammatory bowel disease (IBD) is characterised by significant gastrointestinal tract inflammation. IBD is strongly correlated with extraintestinal symptoms (EIMs). Renal complication is considered as one of the EIMs.
Objective: The current study was done to assess whether patients with inflammatory bowel disease have some degree of renal involvement and also to determine if associated with disease activity or not.
Patients and methods: A cross sectional study included a total of 121 patients who were confirmed to have inflammatory bowel disease were enrolled in the study. Thorough history taking and clinical evaluation of enrolled patients were done. Different data of the patients were gathered based on development of kidney disease
Results: A total of 20 (16.5%) patients were found to have kidney disease. Patients with kidney disease had significantly younger age at time of diagnosis (36.40 ± 9.66 vs. 29.65 ± 8.19) and longer disease duration (2.63 ± 1.28 vs. 4.11 ± 2.47) in comparison to those without kidney disease. Based on the current study, predictors of kidney disease in patients with inflammatory bowel disease were younger age of diagnosis, duration of the disease and family history of chronic disease.
Conclusion: Early detection of these kidney manifestations is of major importance, and regular monitoring of renal function in IBD patients could help guide therapy and eventually reduce the overall morbidity.