Gharib, M., Ali, F., Adly, H., Elkady, H. (2022). Effect of Correction of Metabolic Acidosis on Serum Interleukin 10 Levels in Chronic Hemodialysis Patients. The Egyptian Journal of Hospital Medicine, 88(1), 3029-3032. doi: 10.21608/ejhm.2022.244532
Mohamed Sary Gharib; Fawzia Hassan Ahmed Abo Ali; Heba William Adly; Hossam Moustafa Elkady. "Effect of Correction of Metabolic Acidosis on Serum Interleukin 10 Levels in Chronic Hemodialysis Patients". The Egyptian Journal of Hospital Medicine, 88, 1, 2022, 3029-3032. doi: 10.21608/ejhm.2022.244532
Gharib, M., Ali, F., Adly, H., Elkady, H. (2022). 'Effect of Correction of Metabolic Acidosis on Serum Interleukin 10 Levels in Chronic Hemodialysis Patients', The Egyptian Journal of Hospital Medicine, 88(1), pp. 3029-3032. doi: 10.21608/ejhm.2022.244532
Gharib, M., Ali, F., Adly, H., Elkady, H. Effect of Correction of Metabolic Acidosis on Serum Interleukin 10 Levels in Chronic Hemodialysis Patients. The Egyptian Journal of Hospital Medicine, 2022; 88(1): 3029-3032. doi: 10.21608/ejhm.2022.244532
Effect of Correction of Metabolic Acidosis on Serum Interleukin 10 Levels in Chronic Hemodialysis Patients
Background: Metabolic acidosis is a common complication in chronic hemodialysis (HD) patients and can cause loss of lean body mass. Interleukin 10 (IL-10) also is increased in chronic HD patients and has a prognostic value. Objectives: The aim of this study was to evaluate the effect of correction of metabolic acidosis on serum IL-10 levels in chronic hemodialysis patients. Patients and Methods: Forty chronic hemodialysis patients with predialysis bicarbonate levels Results: Bicarbonate levels significantly increased at end of study (22.83±0.71 vs 18.85±1.12 mEq/l, p < 0.001). Serum IL-10 levels significantly decreased after correction of metabolic acidosis (19.91±6.68 vs 25.89±10.64 pg/ml, p < 0.001) and the change of IL-10 was significantly correlated with the change in bicarbonate (r = - 0.436, p = 0.005). Conclusions: Correction of metabolic acidosis in chronic hemodialysis patients was associated with decrease in serum IL-10.