Role of Tetracycline in Management of Seroma Post-operative in Native Access for Hemodialysis, Post Appendicectomy and Post Mastectomy

Background: Seroma is a frequent surgical complication. Complications include compression of other tissues, infection, and abscesses. Patients with mastectomy, appendicectomy and native access had 4.3%-63% seromas. Seroma commonly occurs after lymphatic channel injury. Tetracycline (TCN) is an antibiotic used to treat illnesses such as acne, cholera, brucellosis, plague, malaria, and syphilis. It is an effective topical sclerosing agent.
Objective: The present study aimed to determine the role of tetracycline in management of post-operative seroma in native access for haemodialysis, post-appendicectomy and post-mastectomy.
Methods: This was a prospective cross-sectional study conducted on 104 patients with post-operative seroma at Minya University Hospital and The Good Shepherd Hospital. All patients provided their demographic information. Locally administered tetracycline to a wound. The patients were monitored for post-operative wound problems and seroma healing.
Results: Native access patients were 44. Mean age was 45.59 ± 16.75 years. 47.7% were females and 52.3% were males. Diabetes prevalence reached 68.2% and HTN prevalence reached 56.8%. Post-appendicectomy patients were 29. Mean Age was 28.5 ± 7.53 years. 41% were females and 46% were males. 33% of patients had diabetes. Appendicular abscess was recognized in 36% of patients. Post-mastectomy patients were 30. Mean age was 56.6 ± 9.49 years. 96.67% were females. 50% of participants had diabetes.
Conclusion: Tetracycline was effective in seroma treatment in most patients with complete improvement in less than 10 days. Only post-mastectomy patients that showed resolve days more than other patients.