Gabr, H., Ghonem, M., Bakir, W. (2022). Assessment of Total Serum Bilirubin Level for Neonatal Jaundice after Intensive Phototherapy. The Egyptian Journal of Hospital Medicine, 88(1), 2742-2745. doi: 10.21608/ejhm.2022.241131
Heba Elsayed Gabr; Moustafa Gamal Amin Ghonem; Wael Husseiny Soliman Bakir. "Assessment of Total Serum Bilirubin Level for Neonatal Jaundice after Intensive Phototherapy". The Egyptian Journal of Hospital Medicine, 88, 1, 2022, 2742-2745. doi: 10.21608/ejhm.2022.241131
Gabr, H., Ghonem, M., Bakir, W. (2022). 'Assessment of Total Serum Bilirubin Level for Neonatal Jaundice after Intensive Phototherapy', The Egyptian Journal of Hospital Medicine, 88(1), pp. 2742-2745. doi: 10.21608/ejhm.2022.241131
Gabr, H., Ghonem, M., Bakir, W. Assessment of Total Serum Bilirubin Level for Neonatal Jaundice after Intensive Phototherapy. The Egyptian Journal of Hospital Medicine, 2022; 88(1): 2742-2745. doi: 10.21608/ejhm.2022.241131
Assessment of Total Serum Bilirubin Level for Neonatal Jaundice after Intensive Phototherapy
Background: Intensive phototherapy in neonatal hyperbilirubinemia rapidly decreases serum total bilirubin (STB) below the threshold for treatment. Intensive phototherapy implies the use of high levels of irradiance to as much of infant's surface area as possible. Objectives: This study aimed to assess the total serum bilirubin level for neonatal jaundice after intensive phototherapy. Patients and Methods: This study was conducted on 200 newborns with neonatal jaundice who were admitted to the NICU of Benha Teaching Hospital, Egypt, requiring double surface, and intensive phototherapy treatment during the period of the study from March 2020 till December 2020. Results: Among the 200 neonates with hyperbilirubinemia, the mean STB measurement at presentation was 12.12 ± 4.6 mg/dl, after phototherapy the mean of STB was 8.4 ± 3.39 mg/dl. After stoppage of phototherapy by 24± 6 hours the mean was 11.34 ± 3.17 mg/dl. The mean STB after phototherapywas 8.4 ± 3.39 mg/dl, while after stoppage by 24 ± 6 hours the mean was 11.34 ± 3.17 mg/dl. There was significant difference between the three measurements regarding present serum total bilirubin, after phototherapy & after stoppage by 24 ± 6 hours (with P < 0.001). Conclusion: Intensive phototherapy in neonatal hyperbilirubinemia rapidly decreases serum total bilirubin (STB) below the threshold for treatment. However, underlying alteration in bilirubin production and excretion may persist and cause bilirubin rebound after stopping phototherapy.