Ibrahim, A., Taha, H., Mohammed, R., Khalil, S., Abd-Allah, N. (2022). Study of Prevalence of Autoimmune Manifestations of Chronic Hepatitis C Infection in Beni-Suef Governorate. The Egyptian Journal of Hospital Medicine, 87(1), 1736-1742. doi: 10.21608/ejhm.2022.229732
Ahmed Amin Ibrahim; Hanan Ali Taha; Rabab Afifi Mohammed; Shahenaz Hamdi El Genedi Khalil; Nilly Abd-Allah. "Study of Prevalence of Autoimmune Manifestations of Chronic Hepatitis C Infection in Beni-Suef Governorate". The Egyptian Journal of Hospital Medicine, 87, 1, 2022, 1736-1742. doi: 10.21608/ejhm.2022.229732
Ibrahim, A., Taha, H., Mohammed, R., Khalil, S., Abd-Allah, N. (2022). 'Study of Prevalence of Autoimmune Manifestations of Chronic Hepatitis C Infection in Beni-Suef Governorate', The Egyptian Journal of Hospital Medicine, 87(1), pp. 1736-1742. doi: 10.21608/ejhm.2022.229732
Ibrahim, A., Taha, H., Mohammed, R., Khalil, S., Abd-Allah, N. Study of Prevalence of Autoimmune Manifestations of Chronic Hepatitis C Infection in Beni-Suef Governorate. The Egyptian Journal of Hospital Medicine, 2022; 87(1): 1736-1742. doi: 10.21608/ejhm.2022.229732
Study of Prevalence of Autoimmune Manifestations of Chronic Hepatitis C Infection in Beni-Suef Governorate
Background: Although most patients with chronic hepatitis C are asymptomatic, an appreciable number will experience symptoms that are due to liver disease and /or extrahepatic manifestations of HCV infection. Recognition of these symptoms will lead to early diagnosis and treatment of hepatitis C. Objective: This study aimed to assess the prevalence of extrahepatic manifestations in patients with chronic hepatitis c infection in Beni-Suef Governorate. Patients and methods: 200 patients with CHC are studied, their ages ranged between 20-60 years. They are collected randomly from Beni-Suef University and general hospitals and outpatient clinics. Results: There is a wide range of prevalence of EHMS of HCV infection, 8% were asymptomatic and accidentally discovered to have HCV. 92% of the total number of patients have at least one EHM. The commonest extrahepatic manifestations are rheumatological 51%, hematological 26%, fatigue 20%, dermatological 19%, neurological 16%, DM11%, cryoglobulinemia 9% and less common chest, renal, lymphoproliferative disorders, cardiac, thyroid dysfunction. Conclusion: Extrahepatic manifestations appear earlier than hepatic manifestations of HCV patients. Age and liver fibrosis are considered major risk factors of EHMs. Health professionals should be aware of these HCV-associated complications and presentations.