Polycystic Ovary Syndrome Phenotypes among Infertile Women in Zagazig University Hospitals

Al Anwar, Amal Mohamed; El Sayed, Mohamed Lotfy Mohamed; Salim, Ameerah Mohammed Alsheebani; Abd Al Salam, Hoda Sibai

doi:10.21608/ejhm.2022.224904

Polycystic Ovary Syndrome Phenotypes among Infertile Women in Zagazig University Hospitals

Document Type : Original Article

Authors

10.21608/ejhm.2022.224904

Abstract

Background: Little studies have been performed to study the different Polycystic Ovary Syndrome (PCOS) phenotypes among infertile women.
Objective: Evaluation the phenotypes of polycystic ovary syndrome among infertile women in Zagazig University Hospitals.
Patients and methods: This study was conducted, as cross-sectional study on 48 infertile women attending Cytogenetic Unit and Ultrasound Unit at Zagazig University Hospital, who were diagnosed with PCOS. They were evaluated by ultrasonography. They were assigned into four phenotypes; A, B, C, and D, on basis of Rotterdam criteria.
Results: The primary infertility was more common among phenotype A, while secondary infertility was more common among phenotypes B and D but without statistical significance difference. There was no statistically significant difference between different types of PCO in prolactin, FSH, free testosterone and cortisol but there was a statistically significant increase in LH among type D in comparison to other types, there was a statistically significant increase in total testosterone among type A in comparison to other types and there was a statistically significant decrease in 17 α -OHP among type D in comparison to other types. There was a statistically significant increase in antral follicle count on right side among type A in comparison to other types and there was a statistically significant increase in antral follicle count on left side among type A and D in comparison to other types.
Conclusion: The study suggests that phenotypic group A is the most prevalent phenotype of PCOS.

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