Short Term Evolution of Left Ventricular Diastolic Function Following Primary Percutaneous Coronary Intervention

Talaat, Ahmed Khaled Muhammed; El-Menshawy, Mahmoud Diaa; El-Zaiat, Ahmed Mohammed; El-Dosouky, Ibtesam

doi:10.21608/ejhm.2022.220740

Short Term Evolution of Left Ventricular Diastolic Function Following Primary Percutaneous Coronary Intervention

Document Type : Original Article

Authors

10.21608/ejhm.2022.220740

Abstract

Background: It is well established fact that acute coronary occlusion leads to diastolic dysfunction, followed by systolic dysfunction when myonecrosis occurs. It is also proven that primary percutaneous coronary intervention (PPCI) is an excellent therapy for ST elevation myocardial infarction (STEMI) to improve outcomes. However there is a paucity of information on efficacy of PPCI in improving diastolic function. Evaluation of the role of PPCI in improving diastolic dysfunction is required. Objective: To evaluate diastolic dysfunction recovery following successful PCI in STEMI patients according to the occluded artery including Left Anterior Descending (LAD) group and Non-LAD group including Left Circumflex Artery (LCX) and Right Coronary Artery (RCA).
Patients and methods: The studyincluded sixty one patients who were presented to emergency room with STEMI and underwent primary PCI. Echocardiographic evaluation was performed within 24 h of PPCI and then on 3 months after PPCI. We evaluated the prevalence of diastolic dysfunction after PPCI and its recovery during 3 months.
Results: There was a significant difference between grading of degree of diastolic dysfunction before PCI and after 3-months follow up with significant improvement after PCI. Conclusion: We concluded that primary PCI improves diastolic dysfunction in patients with anterior wall STEMI over a period of 3 months.

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