Abd-El Moez, A., Mohamed, H., Khalil, A., Ahmed, H. (2022). Assessment of Level of Serum Cardiac Troponin T in Neonates with Respiratory Distress Syndrome. The Egyptian Journal of Hospital Medicine, 86(1), 124-129. doi: 10.21608/ejhm.2022.210784
Amr Ismail Abd-El Moez; HanaaAbd-Elfattah Mohamed; Azza Ali Khalil; Hanan Samir Ahmed. "Assessment of Level of Serum Cardiac Troponin T in Neonates with Respiratory Distress Syndrome". The Egyptian Journal of Hospital Medicine, 86, 1, 2022, 124-129. doi: 10.21608/ejhm.2022.210784
Abd-El Moez, A., Mohamed, H., Khalil, A., Ahmed, H. (2022). 'Assessment of Level of Serum Cardiac Troponin T in Neonates with Respiratory Distress Syndrome', The Egyptian Journal of Hospital Medicine, 86(1), pp. 124-129. doi: 10.21608/ejhm.2022.210784
Abd-El Moez, A., Mohamed, H., Khalil, A., Ahmed, H. Assessment of Level of Serum Cardiac Troponin T in Neonates with Respiratory Distress Syndrome. The Egyptian Journal of Hospital Medicine, 2022; 86(1): 124-129. doi: 10.21608/ejhm.2022.210784
Assessment of Level of Serum Cardiac Troponin T in Neonates with Respiratory Distress Syndrome
Background: One of the most prevalent reasons for admission to neonatal intensive care units (NICUs) is respiratory distress syndrome (RDs). When myocardial cells are damaged, cardiac troponin I (cTnT) is released as a biomarker of myocardial damage, which is very specific and sensitive. Objective: To determine the level of cTnT in preterm infants who have respiratory distress syndrome as a marker of cardiac dysfunction. Patients and Methods: This study was carried as a case-control trial on forty preterm infants, 20 patients of respiratory distress syndrome at neonatal intensive care unit as a group I, 20 apparently healthy newborns as a control group. Serum cardiac troponin T level sample was taken on the 3rd day of delivery. Results: A statistically significant difference in blood troponin was found between the groups tested, with a negative connection between serum troponin and gestational age, length, and APGAR scores at the first and fifth minutes of life.Respiratory rate and serum troponin were found to have a statistically significant connection. Any one of the echocardiographic measures had a statistically significant positive connection with serum troponin. Serum troponin was able to diagnose respiratory distress syndrome with cutoff ≥ 93.5 ng/mL with the area under the curve, Positive predictive value: 83.33% Positive predictive value: 83.33% Negative predictive value: 100 percent Accuracy: 90%. Conclusion: Cardiac troponin T can be used to detect cardiac dysfunction in ill newborns, especially in centers that do not have in-house echocardiography.
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