This work was designed to assess the pharmacological effects of rocuronium. In either isolated preparation or intact animals. Rocuronium (6-96 μg/ml) caused a significant dose related reduction in the amplitude of rat phrenic nerve diaphragm contraction in response to indirect stimulation, the mean percentage reduction were statistically significant. The addition of neostgmine (0.25 μg/ml) caused complete reversal of the relaxant effect of rocuronium . In intact cat gastrocnemius sciatic nerve preparation rocuronium (25 - 200 μg/kg) caused dose dependent statiscally significant reduction. In comparing the drug with succinyl choline by the head drop method the mean time in second was 15.34 ±1.57 and 10.44 ±0.91 respectively.
Gaafary, M. M., & Al. Alkami, E. F. (2001). Rocuronium bromide: a pharmacological study. The Egyptian Journal of Hospital Medicine, 2(1), 1-10. doi: 10.21608/ejhm.2001.18916
MLA
Maaly M.H Gaafary; Essam F. Al. Alkami. "Rocuronium bromide: a pharmacological study", The Egyptian Journal of Hospital Medicine, 2, 1, 2001, 1-10. doi: 10.21608/ejhm.2001.18916
HARVARD
Gaafary, M. M., Al. Alkami, E. F. (2001). 'Rocuronium bromide: a pharmacological study', The Egyptian Journal of Hospital Medicine, 2(1), pp. 1-10. doi: 10.21608/ejhm.2001.18916
VANCOUVER
Gaafary, M. M., Al. Alkami, E. F. Rocuronium bromide: a pharmacological study. The Egyptian Journal of Hospital Medicine, 2001; 2(1): 1-10. doi: 10.21608/ejhm.2001.18916
)
View on SCiNiTO