Evaluation Of Transforming Growth Factor  (Tgf- ) And Epidermal Growth Factor Receptor (Egfr) Expression In Oral Squamous Cell Carcinoma

Document Type : Original Article

Authors

1 Basic Medical Sciences Department

2 Medical Division, National

3 Research Center

Abstract

Objective: The present study aimed to investigate the pattern of expression of transforming growth factor & (TGF-&) and epidermal growth factor receptor (EGFR) in oral squamous cell carcinoma (OSCC) and to correlate their expression with tumor grading.
Conclusion: This study showed that OSCC express both EGFR and TGF-& and their expression indicated that these markers may have a potential diagnostic value in histologic examination. In addition their increased expression in high tumour grades suggest that they may be used as indicators of tumor aggressiveness.

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