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Abbas, E., Abdel-Aal, W., Samy, A. (2002). Evaluation Of Transforming Growth Factor  (Tgf- ) And Epidermal Growth Factor Receptor (Egfr) Expression In Oral Squamous Cell Carcinoma. The Egyptian Journal of Hospital Medicine, 7(1), 168-176. doi: 10.21608/ejhm.2002.18849
Effat A. Abbas; Wafaa E. Abdel-Aal; Aml A. Samy. "Evaluation Of Transforming Growth Factor  (Tgf- ) And Epidermal Growth Factor Receptor (Egfr) Expression In Oral Squamous Cell Carcinoma". The Egyptian Journal of Hospital Medicine, 7, 1, 2002, 168-176. doi: 10.21608/ejhm.2002.18849
Abbas, E., Abdel-Aal, W., Samy, A. (2002). 'Evaluation Of Transforming Growth Factor  (Tgf- ) And Epidermal Growth Factor Receptor (Egfr) Expression In Oral Squamous Cell Carcinoma', The Egyptian Journal of Hospital Medicine, 7(1), pp. 168-176. doi: 10.21608/ejhm.2002.18849
Abbas, E., Abdel-Aal, W., Samy, A. Evaluation Of Transforming Growth Factor  (Tgf- ) And Epidermal Growth Factor Receptor (Egfr) Expression In Oral Squamous Cell Carcinoma. The Egyptian Journal of Hospital Medicine, 2002; 7(1): 168-176. doi: 10.21608/ejhm.2002.18849

Evaluation Of Transforming Growth Factor  (Tgf- ) And Epidermal Growth Factor Receptor (Egfr) Expression In Oral Squamous Cell Carcinoma

Article 14, Volume 7, Issue 1, April 2002, Page 168-176  XML PDF (379.87 K)
Document Type: Original Article
DOI: 10.21608/ejhm.2002.18849
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Authors
Effat A. Abbas1; Wafaa E. Abdel-Aal2; Aml A. Samy3
1Basic Medical Sciences Department
2Medical Division, National
3Research Center
Abstract
Objective: The present study aimed to investigate the pattern of expression of transforming growth factor & (TGF-&) and epidermal growth factor receptor (EGFR) in oral squamous cell carcinoma (OSCC) and to correlate their expression with tumor grading.
Conclusion: This study showed that OSCC express both EGFR and TGF-& and their expression indicated that these markers may have a potential diagnostic value in histologic examination. In addition their increased expression in high tumour grades suggest that they may be used as indicators of tumor aggressiveness.
Keywords
Oral squamous cell carcinoma; Epidermal growth factor receptor; transforming growth factor-& and immunohistochemistry
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