Studies On Some Technological Factors Affecting Some Veterinary Drug Residues In Buffalo's Milk

El-Behairy, S.A.; Radwan, U.M.; M.A, El-Nawawy,; Mohamed, Mona A.H.

doi:10.21608/ejhm.2005.18062

Studies On Some Technological Factors Affecting Some Veterinary Drug Residues In Buffalo's Milk

Document Type : Original Article

Authors

¹ Food Evaluation and Food Sci. Dept., National Organization for Drug Control and Research (NODCAR), Giza, Egypt.

² Agric. Dept., Inst. Of Environmental Studies and Research, Ain Shams Univ

³ Food Sci. Dept., Fac. of Agric., Ain Shams Univ.

10.21608/ejhm.2005.18062

Abstract

In the present study a suggested rapid method for detection of some veterinary drug residues namely ciprofloxacin, ivermectin and triclabendazole in milk and studied the effect of some technological factors on the residues of such drugs in buffalo's milk. The suggested method depends on the extraction of previously mentioned drugs by dialysis through a membrane in suitable solvent, then measuring the absorbance spectrophotometrically at 278, 243 and 307 n.m. respectively.
Ciprofloxacin is bounded to milk while ivermectin and triclabendazole are completely dissolved in the cream layer.
Data indicated that these drugs showed high thermal, salt concentration up to 20% and pH stability. Therefore these veterinary drugs can be a hazard source in milk retentate, concentrated milk, cheese or other concentrated milk protein products (Entriquez, 2000). Thus application of HACCP system in milk production and processing must be taken into consideration to ensure a safe product for the consumer.