Biological studies on fresh water snails target to Schistosoma mansoni infection

Abdel – Hamid, Abdel – Hamid Z.; Abd El – Wahab, Samia M.; El – Tonsy, Mona M.; Abdel – Megeed, Rehab M.

doi:10.21608/ejhm.2006.17912

Biological studies on fresh water snails target to Schistosoma mansoni infection

Document Type : Original Article

Authors

¹ Medicinal Chemistry Department , National Research Center

² Zoology Department , Faculty of Science , Al – Azhar University for Girls , Cairo , Egyp

10.21608/ejhm.2006.17912

Abstract

Inthisstudy,uponexposureoflaboratoryEgyptianB.alexandrinaandB.glabratasnailsto itshomologusstrainofS.mansoni,twodifferentphenotypestrains"susceptibleandresistant" weredistinguished.Theaimofthisstudyistoinvestigatethebiologicaldifferencesbetween thetwotypesofBiomphalariasnailseithersusceptibleorresistantatdifferentages.The investigatedparametersincludedmortality,survival,percentageofsusceptibility/resistanceto parasiticinfectionandfecundity.Theresultsofthepreliminaryexposureexperimentrevealed thatparentalsnailstockwasnotcompletelysusceptibleandtendtobepartiallyrefractoryto infection.Theresultsalsoshowedastrongassociationbetweenthelevelsofeggproduction andsusceptibilitytoparasiteinfection.Wherebreedingexperimentrevealedthat,totalegg number,E/MandEMvaluesproducedbyresistantphenotypeofbothsnailspeciesweremore thanthoseproducedbysusceptibleprogenysnails.Also,itwasnoticedthat,eggproductionis associatedinverselyproportionwithsnailage.