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Eraba, K., Khedr, E., Atia, T., Mourad, S. (2007). Histological Study Of The Influence Of Bioactive Glass On Bone Healing (An Experimental Study On Rat Femur). The Egyptian Journal of Hospital Medicine, 29(1), 672-684. doi: 10.21608/ejhm.2007.17709
K. M.T. Eraba; Elsayed G. Khedr; Tarek A. Atia; Salah E. Mourad. "Histological Study Of The Influence Of Bioactive Glass On Bone Healing (An Experimental Study On Rat Femur)". The Egyptian Journal of Hospital Medicine, 29, 1, 2007, 672-684. doi: 10.21608/ejhm.2007.17709
Eraba, K., Khedr, E., Atia, T., Mourad, S. (2007). 'Histological Study Of The Influence Of Bioactive Glass On Bone Healing (An Experimental Study On Rat Femur)', The Egyptian Journal of Hospital Medicine, 29(1), pp. 672-684. doi: 10.21608/ejhm.2007.17709
Eraba, K., Khedr, E., Atia, T., Mourad, S. Histological Study Of The Influence Of Bioactive Glass On Bone Healing (An Experimental Study On Rat Femur). The Egyptian Journal of Hospital Medicine, 2007; 29(1): 672-684. doi: 10.21608/ejhm.2007.17709

Histological Study Of The Influence Of Bioactive Glass On Bone Healing (An Experimental Study On Rat Femur)

Article 17, Volume 29, Issue 1, October 2007, Page 672-684  XML PDF (866.04 K)
Document Type: Original Article
DOI: 10.21608/ejhm.2007.17709
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Authors
K. M.T. Eraba1; Elsayed G. Khedr2; Tarek A. Atia2; Salah E. Mourad3
1Faculty Of Science, Department Of Physics Al Azhar University
2Faculty Of Medicine, Departments Of Histology
3Faculty Of Science, Department Of Anatomy,Al Azhar University
Abstract
The objective is to study the histological influence of the bioactive glass on bone healing in surgically created holes in rat’s femur.
Methods: The two wall holes were made in the right femurs by 2-mm drill, filled with bioactive glass in the examined rats. Another two wall holes were made similarly in the right femurs of other group of rats without filling with bioactive glass and used as the control group. Animals were regularly examined over a period of five weeks for bone healing.
Result: Histological examination of both control and treated sites showed newly formed bone. The newly formed ostoid tissue was significantly increased in the treated holes in the form of foci of newly formed bone around and within the glass particles. In the control group, the junctional epithelium migrated up to the base of the hole.
Conclusion: The treated animals with bioactive glass had better healing than control. The bioactive glass particles have osteo-conductive property as well as osteo-stimulatory capacity. The graft material showed a promising inhibition of greater cementum deposition in the bone holes. We can use it in Osteosurgery as it can promote bone healing.
 
Keywords
Bioactive glass; bone hole; bone healing; histological changes
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