Effects Of Orally Fed Diazinon On Some Biochemical Parameters Of Male Albino Rats

Document Type : Original Article

Author

Biological and Geological Sciences Department , Faculty of Education , Ain Shams University , Cairo , Egypt .

Abstract

Background:The current investigation was carried out to study the effect of orally administration of diazinon insecticide on some biochemical blood indices on male albino rats.
Material and methods: The organophosphorus insecticide , diazinon was orally administrated at a dose
(100mg/kg body weight=1/3LD50) , daily for 10 days (short
term) and 20 days (long term) to adult male albino rats .
Results: The results revealed the following:


1-  Diazinon led to an increase in rat blood serum glucose& T3 (short and long term);
AST,ALT, and T4 (long-term).


2-  Diazinon reduced the serum content of total cholesterol and protein in shortterm
treated rats.


3-  Treatment of rats with diazinon did not alter activity of AST, ALT and T4 level at
short term period .In addition ; ALP serum levels were not altered in both short and long term treated rats .
 

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