Allergic bronchopulmonary aspergillosis among patients with bronchial asthma

M, Al-Najada; K, Al-Nadi; AM, Sharara

doi:10.21608/ejhm.2018.16971

Allergic bronchopulmonary aspergillosis among patients with bronchial asthma

Document Type : Original Article

Authors

Department of chest disease, King Hussein Medical Centre, amman -jordan

10.21608/ejhm.2018.16971

Abstract

Objective
To determine the different presentations encountered upon diagnosis of ABPA among patients with bronchial asthma and the two-year-follow-up results.
Patients and method
All patients with bronchial asthma and ABPA were included in the study .Specially formulated sheet was done include age, gender, duration of bronchial asthma ,new clinical,radiological,and laboratory findings suggestive of ABPA and two year follow up of them. Diagnosis of ABPA was based on Rosenberg-Patterson criteria.
Result
Fifteen patients with ABPA 3.9% out of 385 patients with bronchial asthma were included in our study, (5males)and (10 females) there mean age was 28.8 years , and mean duration of asthma was 8.9 years, and they represent all stages of asthma severity. Fleeting shadows mainly in the upper lobes were the most common radiological findings observed in nine patients (60%), five patients (33.3%) had proximal bronchiectasis detected by high resolution chest ct-scan, one of our patients had collapsed consolidation. All patients had moderate to severe eosinophilia and positive immediate skin test for aspergillus.
Conclusion
As the prevalence of ABPA is not uncommon among patients with bronchial asthma regardless the severity and the level control of asthma, high index of suspicious for ABPA should be maintained when followed up any patient with bronchial asthma.