Effect of Noise and Crowding Related Stress on Serum Level of Cortisol ACTH, Epinephrine and Insulin in Female Albino Rats

Helal, Eman G. E.; Abou-Aouf, Noran Ahmed; Taha, Neama M.

doi:10.12816/0004510

Effect of Noise and Crowding Related Stress on Serum Level of Cortisol ACTH, Epinephrine and Insulin in Female Albino Rats

Document Type : Original Article

Authors

¹ Zoology Department, Faculty of Science, Al-Azhar University (girls)

² Zoology Department, Faculty of Science, Al-Azhar University (girls

10.12816/0004510

Abstract

Background: Noise and crowdingare the most stressful factors for human beings.
Study aimed to clarify their effect on cortisol, ACTH, epinephrine, insulin and the amelioration effect of Sulpiride.
Material and Methods: Thirty six female rats were divided into six groups (6/each):
1- Rats served ascontrol, 2- Rats treated with Sulpiride drug, 3- Rats exposed to noise (90db, 3hr. per day) for 45 days. 4- Rats exposed to noise and treated with sulpiride drug, 5- Rats exposed to crowding. 6- Rats exposed to noise and treated with Sulpiride drug.
Results: Noise and crowding stresses caused a significant increase of cortisol, ACTH and epinephrine while there was a significant decrease in insulin hormone. Sulpiride drug ameliorated these parameters.
Conclusion: it is useful to use Sulpiride drug with people who are exposing to noise and crowding stress.

Keywords