Screening For Antiviral Activities of Aqueous Extracts of Some Egyptian Seaweeds

Zaid, Shaimaa Ashour Abdel-Latif; Abdel-Wahab, Kouka Saad El-Din; Abed, Nermine N.; Abo El-Magd, Enas Kamal; Salah El-Din, Rawheya Abdel-Latif

doi:10.12816/0029035

Screening For Antiviral Activities of Aqueous Extracts of Some Egyptian Seaweeds

Document Type : Original Article

Authors

¹ Microbiologist at Chemistry Administration, Ministry of Trade and Industry

² Microbiology Department, Faculty of Medicine for Girls, Al-Azhar University

³ Botany and Microbiology Department, Faculty of Science for Girls, Al-Azhar University

10.12816/0029035

Abstract

Background: aqueous extracts of six species of marine seaweed were studied as antiviral activity on different viruses. Materials and methods: these collected from two sites Hurghada at the Red Sea and Al-Agami area in Alexandria Mediterranean Sea Egypt and belonging to the classes Chlorophyta, Phaeophyta and Rhodophyta were assayed for the cytotoxicity and antiviral activity by MTT [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenlytetrezolium bromide] and by neutralization methods.
Results: these extracts have antiviral activity to herpes simplex virus types-1 (HSV-1) and type-2 (HSV-2), hepatitis A virus (HAV-H₁₀), and Coxsackie B₄ virus in Vero cells with very low cytotoxicity to the host cells.

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