El-Shahawy, H., Hendawy, S., Hassanin, A., Abd El-Azeem, M. (2017). Estimation of Serum Ferritin Level in Preterm Labour. The Egyptian Journal of Hospital Medicine, 68(3), 1469-1474. doi: 10.12816/0039690
Hazem F. El-Shahawy; Sherif F. Hendawy; Alaa S. Hassanin; Mona M. Abd El-Azeem. "Estimation of Serum Ferritin Level in Preterm Labour". The Egyptian Journal of Hospital Medicine, 68, 3, 2017, 1469-1474. doi: 10.12816/0039690
El-Shahawy, H., Hendawy, S., Hassanin, A., Abd El-Azeem, M. (2017). 'Estimation of Serum Ferritin Level in Preterm Labour', The Egyptian Journal of Hospital Medicine, 68(3), pp. 1469-1474. doi: 10.12816/0039690
El-Shahawy, H., Hendawy, S., Hassanin, A., Abd El-Azeem, M. Estimation of Serum Ferritin Level in Preterm Labour. The Egyptian Journal of Hospital Medicine, 2017; 68(3): 1469-1474. doi: 10.12816/0039690
Estimation of Serum Ferritin Level in Preterm Labour
1Obstetrics and Gynecologydepartment, Faculty of Medicine,Ain Shams University, Egypt
2Department of Obstetrics and Gynecology Alex. Governorate Obstetric Hospital, (Dar Ismail Hospital), Egypt.
Abstract
Background: Preterm birth is the leading cause of newborn deaths and also the leading cause of death in children under 5 years of age. There is wide spread suspicion that subclinical infection is a common accompaniment and cause of preterm labour. Ferritin is an acute phase reactant and it increases during inflammation. Aim: The objective of this study is to measure serum ferritin level in cases of established preterm labour (PTL) as a possible marker of infection. Study Setting: This study conducted at Ain Shams University Maternity Hospital from March 2015 to November 2015. Study design: A case-control study. Patients and Methods: The study involved 2 groups. Study population: 60 cases divided into two groups:
Group (I): included 30 patients with established (PTL) between 30 to 34 weeks gestational age (GA). Group (II): (Control group) 30 patients with uncomplicated pregnancies between 30 to 34 weeks GA. Serum ferritin was analyzed in the 2 groups.
Results: The results pointed out that there was statistically significant difference between two groups as regarding serum ferritin level as p value was <0.0001 . The median serum ferritin level in preterm labour group and control group was 150 (100 – 150) ng/ml and 20 (15 – 25) ng/ml respectively. The best cut off value of serum ferritin as predictor of preterm labour was >55 ng/ml with a sensitivity of 96.7% and specificity of 96.7 %. Conclusion: Serum ferittin can be used as a marker of preterm labour.
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