Abdel-Rahim, M., Attia, T., Abdel-Rahman, D. (2020). Non-Invasive Ventilation in Preventing Intubation and Reintubation in The Intensive Care Unit of Pediatrics Zagazig University Hospital. The Egyptian Journal of Hospital Medicine, 81(7), 2422-2428. doi: 10.21608/ejhm.2020.133658
Mohamed Mohamed Abdel-Rahim; Tarek Abdel-Rahman Mohamed Attia; Dalia Abdel-Latif Abdel-Rahman. "Non-Invasive Ventilation in Preventing Intubation and Reintubation in The Intensive Care Unit of Pediatrics Zagazig University Hospital". The Egyptian Journal of Hospital Medicine, 81, 7, 2020, 2422-2428. doi: 10.21608/ejhm.2020.133658
Abdel-Rahim, M., Attia, T., Abdel-Rahman, D. (2020). 'Non-Invasive Ventilation in Preventing Intubation and Reintubation in The Intensive Care Unit of Pediatrics Zagazig University Hospital', The Egyptian Journal of Hospital Medicine, 81(7), pp. 2422-2428. doi: 10.21608/ejhm.2020.133658
Abdel-Rahim, M., Attia, T., Abdel-Rahman, D. Non-Invasive Ventilation in Preventing Intubation and Reintubation in The Intensive Care Unit of Pediatrics Zagazig University Hospital. The Egyptian Journal of Hospital Medicine, 2020; 81(7): 2422-2428. doi: 10.21608/ejhm.2020.133658
Non-Invasive Ventilation in Preventing Intubation and Reintubation in The Intensive Care Unit of Pediatrics Zagazig University Hospital
1Resident of Pediatrics, Maghagha General Hospital, Minya, Egypt.
2Pediatric Department, Faculty of Medicine, Zagazig University, Sharkia, Egypt.
Abstract
Background: Non-invasive ventilation (NIV) refers to methods of respiratory assistance without an indwelling endotracheal tube. Objectives: To evaluate the efficacy, identify possible predictors for the success of NIV in preventing intubation and re-intubation, and to determine the characteristics, and outcomes associated with NIV therapy in Pediatric intensive care units (PICUs) settings. Patients and Methods: A clinical trial study was conducted at the Pediatric Intensive Care Units, Children Hospital, Zagazig University and Al-Ahrar Educational Hospital on 60 patients divided equally into two groups; group A with NIV as the first line and group B with NIV after extubation. Patients were followed up till weaning. Results: Male constituted a larger percentage with both groups. One-sixth and 20% of patients within group A and B respectively had failed to wean. There is a statistically significant difference between the outcome of weaning among group A and all of PIM-2 score, PIM-2 percent, and NIV duration. While the relation is significant between the outcome of weaning among group B and patients’ age, body weight, and NIV duration. Increasing NIV duration significantly predicts weaning success in group A while increasing body weight predicts it in group B. Conclusion: Non-invasive ventilation as the first line of treatment in acute respiratory failure provides significant avoidance of intubation and lowers the incidence and risk of complications. Non-invasive ventilation if considered after weaning of invasive mechanical ventilation it helps to avoid re-intubation and failure of weaning. The most important significant predictors of NIV outcome are NIV duration and body weight.