Abd El-Hamid, A., Zahran, E., Salim, M. (2020). Chronic Graft-versus-Host Disease: An Immunologic Perspective. The Egyptian Journal of Hospital Medicine, 81(6), 2285-2290. doi: 10.21608/ejhm.2020.131138
Alaa E. Abd El-Hamid; Enas S. Zahran; Mohamed E. Salim. "Chronic Graft-versus-Host Disease: An Immunologic Perspective". The Egyptian Journal of Hospital Medicine, 81, 6, 2020, 2285-2290. doi: 10.21608/ejhm.2020.131138
Abd El-Hamid, A., Zahran, E., Salim, M. (2020). 'Chronic Graft-versus-Host Disease: An Immunologic Perspective', The Egyptian Journal of Hospital Medicine, 81(6), pp. 2285-2290. doi: 10.21608/ejhm.2020.131138
Abd El-Hamid, A., Zahran, E., Salim, M. Chronic Graft-versus-Host Disease: An Immunologic Perspective. The Egyptian Journal of Hospital Medicine, 2020; 81(6): 2285-2290. doi: 10.21608/ejhm.2020.131138
Chronic Graft-versus-Host Disease: An Immunologic Perspective
Department of Internal Medicine, Faculty of Medicine, Menoufia University
Abstract
Background: Chronic graft-versus-host disease (GVHD) is the leading cause of late, nonrelapse mortality and disability in allogeneic hematopoietic cell transplantation recipients and a major obstacle to improving outcomes. The biology of chronic GVHD remains enigmatic, but understanding the underpinnings of the immunologic mechanisms responsible for the initiation and progression of disease is fundamental to developing effective prevention and treatment strategies. Objectives: The aim of this work is to summarize the most recent available data concerning chronic graft versus host disease from biologic, cytogenic and immunopathogenesis and its role in diagnostics therapeutic.
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