Abed, N., Negm, F., Ahmad, E., Mohammed, H. (2020). Vitamin D Levels in Full-Term Neonates with Indirect Hyperbilirubinemia. The Egyptian Journal of Hospital Medicine, 81(5), 2030-2035. doi: 10.21608/ejhm.2020.124800
Neveen T. Abed; Farida F. Negm; Enas S. Ahmad; Heba A. Mohammed. "Vitamin D Levels in Full-Term Neonates with Indirect Hyperbilirubinemia". The Egyptian Journal of Hospital Medicine, 81, 5, 2020, 2030-2035. doi: 10.21608/ejhm.2020.124800
Abed, N., Negm, F., Ahmad, E., Mohammed, H. (2020). 'Vitamin D Levels in Full-Term Neonates with Indirect Hyperbilirubinemia', The Egyptian Journal of Hospital Medicine, 81(5), pp. 2030-2035. doi: 10.21608/ejhm.2020.124800
Abed, N., Negm, F., Ahmad, E., Mohammed, H. Vitamin D Levels in Full-Term Neonates with Indirect Hyperbilirubinemia. The Egyptian Journal of Hospital Medicine, 2020; 81(5): 2030-2035. doi: 10.21608/ejhm.2020.124800
Vitamin D Levels in Full-Term Neonates with Indirect Hyperbilirubinemia
1Department of Pediatrics, Faculty of Medicine, Benha University, Egypt
2Department of Clinical and Chemical Pathology, Faculty of Medicine, Benha University, Egypt
Abstract
Background: Jaundice is a common clinical sign in neonatal medicine. Considering the different roles of vitamin D, its lower level may be correlated with neonatal jaundice. Objectives: This study aimed to demonstrate the relationship between serum vitamin D level and neonatal hyperbilirubinemia and to measure its level in their mothers. Subjects and methods: This case-control study was conducted on 90 neonates and their mothers, 60 neonates with hyperbilirubinemia in patients group and 30 healthy neonates age and sex matched in control group < /span>. Blood samples from neonates and their mothers were obtained and sent for laboratory estimation of 25-hydroxy vitamin D, calcium, magnesium, phosphorus, alkaline phosphatase and parathyroid hormone. Results: There is highly significant decrease of vitamin D levels among patients than controls, significant negative correlation between vitamin D levels and serum bilirubin in neonates and no significant difference regarding different laboratory parameters among their mothers. Conclusion: Decreased levels of vitamin D were significantly correlated with neonatal indirect hyperbilirubinemia so, low vitamin D can be included among risk factors for neonatal jaundice.