Relation between Iron Deficiency and Susceptibility to Bacterial Infections

Alqeaid, Fahad Abdullah R; Dakhel, Abdullah Khalid A

doi:10.12816/0041696

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The Egyptian Journal of Hospital Medicine

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	Relation between Iron Deficiency and Susceptibility to Bacterial Infections
Article 18, Volume 69, Issue 5, October 2017, Page 2469-2475 PDF (315.35 K)
Document Type: Original Article
DOI: 10.12816/0041696
View on SCiNiTO
Authors
Fahad Abdullah R Alqeaid; Abdullah Khalid A Dakhel
Qassim College of Medicine, Qassim - Alrass city
Abstract
Iron deficiency (ID) is a common deficit of the particular nutrient in the body and the top-ranking cause of anemia worldwide. It is a common cause of morbidity and accounts for 50% of anemia cases in the world. Symptoms of iron deficiency are subtle and nonspecific including severe anemia, fatigue, diminished work, gastrointestinal disturbances, associated with the impaired natural type of immunity and the cell-mediated type of immunity. Therefore, differentiating the term iron deficiency and the other term infection is essential. The process by which the microbes acquires iron supplement and the respectful virulence can be identified by the application of the different type of host mechanisms and also different microbial mechanisms, thus interfering with these respective mechanisms is likely to create the future therapy forms for the bacterial diseases that are infectious. In this review article, we summarized the mechanism of iron metabolism in the body, the characteristics of iron deficiency anemia, symptoms, epidemiology and etiology, host mechanism during bacterial infection, and the susceptibility to bacterial invasion in case of iron deficiency anemia.
Keywords
Anemia; iron deficiency anemia, bacterial infection, iron, immunity


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