Khairy, H., Mohamed, M., Hussain, S., Al-Refaie, M. (2017). Value of Glycosylated Hemoglobin at 34 Weeks Gestation in the Prediction of Adverse Neonatal Outcome. The Egyptian Journal of Hospital Medicine, 69(2), 1880-1888. doi: 10.12816/0040617
Hassan T. Khairy; Mohamed E. Mohamed; Sherif H. Hussain; Mohamed S. Al-Refaie. "Value of Glycosylated Hemoglobin at 34 Weeks Gestation in the Prediction of Adverse Neonatal Outcome". The Egyptian Journal of Hospital Medicine, 69, 2, 2017, 1880-1888. doi: 10.12816/0040617
Khairy, H., Mohamed, M., Hussain, S., Al-Refaie, M. (2017). 'Value of Glycosylated Hemoglobin at 34 Weeks Gestation in the Prediction of Adverse Neonatal Outcome', The Egyptian Journal of Hospital Medicine, 69(2), pp. 1880-1888. doi: 10.12816/0040617
Khairy, H., Mohamed, M., Hussain, S., Al-Refaie, M. Value of Glycosylated Hemoglobin at 34 Weeks Gestation in the Prediction of Adverse Neonatal Outcome. The Egyptian Journal of Hospital Medicine, 2017; 69(2): 1880-1888. doi: 10.12816/0040617
Value of Glycosylated Hemoglobin at 34 Weeks Gestation in the Prediction of Adverse Neonatal Outcome
Department of Gynecology, Faculty of Medicine, Ain Shams University
Abstract
Background: Gestational diabetes is diabetes, or high blood sugar levels, that develops during pregnancy.
It occurs in about 4% of all pregnancies. It is usually diagnosed in the later stages of pregnancy and often occurs in women who have no prior history of diabetes. Aim of the Work: To assess the predictive value of elevated glycosylated hemoglobin at 34 weeks’ gestation with adverse fetal outcome as regard fetal macrosomia and neonatal hypoglycemia. Patients and Methods: This prospective longitudinal cohort study included 98 pregnant women who were recruited from the obstetric outpatient clinic and department at Al-Galaa Teaching Hospital. Results: HbA1c ≥7.9 has sensitivity of 88.1% and specificity of 66.1%, in prediction of macrosomia and a sensitivity of91.9% and specificity of 63.9% in prediction of Hypoglycemia. Conclusion: HbA1c ≥7.9 has moderate diagnostic characteristics in prediction ofmacrosomia, and hypoglycemia, low diagnostic characteristics in prediction of RDS and NICU. Recommendations: Use of HbA1C is recommended for patients with GDM for screening, follow up and prediction of adverse neonatal outcomes.