Mohamed, A., abdel Fattah, N., Ismail, W., Abdel-Latif, E. (2020). Occult Hepatitis B Virus Infection Among Hemodialysis Patients in Fakous General Hospital. The Egyptian Journal of Hospital Medicine, 81(3), 1648-1653. doi: 10.21608/ejhm.2020.117022
Asmaa Sobhy Mohamed; Nermien Raaft abdel Fattah; Waleed Abdulfattah Ismail; Emad Abdel-Latif. "Occult Hepatitis B Virus Infection Among Hemodialysis Patients in Fakous General Hospital". The Egyptian Journal of Hospital Medicine, 81, 3, 2020, 1648-1653. doi: 10.21608/ejhm.2020.117022
Mohamed, A., abdel Fattah, N., Ismail, W., Abdel-Latif, E. (2020). 'Occult Hepatitis B Virus Infection Among Hemodialysis Patients in Fakous General Hospital', The Egyptian Journal of Hospital Medicine, 81(3), pp. 1648-1653. doi: 10.21608/ejhm.2020.117022
Mohamed, A., abdel Fattah, N., Ismail, W., Abdel-Latif, E. Occult Hepatitis B Virus Infection Among Hemodialysis Patients in Fakous General Hospital. The Egyptian Journal of Hospital Medicine, 2020; 81(3): 1648-1653. doi: 10.21608/ejhm.2020.117022
Occult Hepatitis B Virus Infection Among Hemodialysis Patients in Fakous General Hospital
Department of Internal Medicine, Faculty of Medicine, Zagazig University, Sharkia, Egypt
Abstract
Background: Occult HBV infection (OBI) is defined as the presence of a small amount of HBV in patients with negative serum for hepatitis B surface antigen (HBs Ag). The serum HBV DNA level in these patients is generally lower than 104 copies/mL, there is a high prevalence of OBI in patients with chronic hepatitis C, HCC cryptogenic liver disease, and HIV. Objectives: Assessment of prevalence of Occult Hepatitis B Virus infection among hemodialysis patients in Fakous General Hospital.
Patients and Methods: A total of 40 patients with end-stage renal disease undergoing regular HD (for at least 6 months underwent a complete physical examination. Serum samples were collected between before hemodialysis and then
stored at -80C° until tested. Serological markers of HBV infection (HBsAg, anti-HBs, anti-HBc) were determined using standard third generation commercially available enzyme immunoassays). Results: The 40 patients who have been included in this study had a minimum age of 25 years and a maximum age of 78 years. The number of females was 25 with a percentage of 62.5% and the percentage of males was about 37.5% (15 males). 22 patients (55%) had negative sera for anti-HCV antibody and a percentage of 37% and 63% for the distribution of females and males, respectively. 18 patients (45%) had positive sera for anti-HCV antibody and 37% of them were females and 63% of them were males. Conclusions: OBI infection is a relatively common infection (37.5%) among chronic hemodialysis patients in the dialysis unit of Fakous general hospital.