Elsayed, Y., Abd Elsalam, W., Ahmed, M., El-Sayyad, A. (2020). Prediction of Maturation of The Fetal Lung by Lamellar Bodies’ Count of Amniotic Fluid in PPROM. The Egyptian Journal of Hospital Medicine, 81(3), 1576-1582. doi: 10.21608/ejhm.2020.115639
Yossef Abu Elwan Elsayed; Walid Abdallah Abd Elsalam; Mostafa Abdou Ahmed; Ahmed Mohamed Mahmoud El-Sayyad. "Prediction of Maturation of The Fetal Lung by Lamellar Bodies’ Count of Amniotic Fluid in PPROM". The Egyptian Journal of Hospital Medicine, 81, 3, 2020, 1576-1582. doi: 10.21608/ejhm.2020.115639
Elsayed, Y., Abd Elsalam, W., Ahmed, M., El-Sayyad, A. (2020). 'Prediction of Maturation of The Fetal Lung by Lamellar Bodies’ Count of Amniotic Fluid in PPROM', The Egyptian Journal of Hospital Medicine, 81(3), pp. 1576-1582. doi: 10.21608/ejhm.2020.115639
Elsayed, Y., Abd Elsalam, W., Ahmed, M., El-Sayyad, A. Prediction of Maturation of The Fetal Lung by Lamellar Bodies’ Count of Amniotic Fluid in PPROM. The Egyptian Journal of Hospital Medicine, 2020; 81(3): 1576-1582. doi: 10.21608/ejhm.2020.115639
Prediction of Maturation of The Fetal Lung by Lamellar Bodies’ Count of Amniotic Fluid in PPROM
Department of Obstetrics and Gynecology, Faculty of Medicine – Zagazig University
Abstract
Background: There are many risk factors for Preterm Premature Rupture of Membranes (PPROM). Infection is the main one (15-25%), especially at earlier gestational ages. Neonatal respiratory distress syndrome of the neonate is an important obstacle in cure of preterm infants. Objective: To assess the efficacy of the amniotic fluid lamellar body counting (LBC) from vaginal pool in predicting fetal lung maturity in women with preterm premature rupture of membranes. Patients and Methods: This study was conducted on 92 cases. Prediction of fetal lung maturity and the presence of respiratory distress syndrome (RDS) were estimated. LBC was measured for all cases. Results: There were a significant negative correlation between respiratory distress syndrome and gestational age. Also a significant correlation between level of LBC and fetal lung maturity using 38.0 (x103 /μL) as a cutoff point for LBC; as it is can be considered a good predictor for fetal lung maturity with sensitivity 92.9% and specificity 90.6%, positive predictive value of 81.3% and negative predictive value of 96.7%. Conclusion: There is a significant correlation between level of LBC and fetal lung maturity. LBC could be considered a good predictor for fetal lung maturity.