Al Hussaini, H. (2020). Steroid-Responsive Encephalopathy Associated with Autoimmune Thyroiditis (SREAT): A Case Report. The Egyptian Journal of Hospital Medicine, 81(1), 1231-1233. doi: 10.21608/ejhm.2020.112309
Hessah Abdulaziz Al Hussaini. "Steroid-Responsive Encephalopathy Associated with Autoimmune Thyroiditis (SREAT): A Case Report". The Egyptian Journal of Hospital Medicine, 81, 1, 2020, 1231-1233. doi: 10.21608/ejhm.2020.112309
Al Hussaini, H. (2020). 'Steroid-Responsive Encephalopathy Associated with Autoimmune Thyroiditis (SREAT): A Case Report', The Egyptian Journal of Hospital Medicine, 81(1), pp. 1231-1233. doi: 10.21608/ejhm.2020.112309
Al Hussaini, H. Steroid-Responsive Encephalopathy Associated with Autoimmune Thyroiditis (SREAT): A Case Report. The Egyptian Journal of Hospital Medicine, 2020; 81(1): 1231-1233. doi: 10.21608/ejhm.2020.112309
Steroid-Responsive Encephalopathy Associated with Autoimmune Thyroiditis (SREAT): A Case Report
Department of Internal Medicine, College of Medicine, King Faisal University, Al Ahsa, Kingdom of Saudi Arabia
Abstract
Background: Steroid-responsive encephalopathy associated with autoimmune thyroiditis (SREAT), also known as Hashimoto’s encephalopathy, is a disorder characterized by an encephalopathy associated with anti-thyroid antibodies in the absence of alternative causes. It has a wide range of clinical, laboratory and radiological features. Objective: Cases of steroid-responsive encephalopathy associated with autoimmune thyroiditis are difficult to diagnose and requires a high index of suspicion, as this will determine the early timing of management and disease outcome. Patient and Methods: Here we present a case report of twenty-year-old woman presenting with neurological and psychological symptoms. She was found to have high anti-thyroid peroxidase antibodies (Anti-TPO) with normal thyroid function and negative screening for other etiologies of encephalopathy. Based on her presentation, she was diagnosed with steroid-responsive encephalopathy associated with autoimmune thyroiditis. Results: Patient was started on high dose steroids upon which she responded partially. Then she required the addition of immunotherapy in the form of Rituximab to improve her symptoms. Conclusion: After exclusion of other causes of encephalopathy, the presence of thyroid antibodies prompts the susp < /span>icion of SREAT and therefore the early initiation of steroids to improve patients’ outcome.