Home Articles List Article Information
The Egyptian Journal of Hospital Medicine
Journal Archive
Volume Volume 97 (2024)
Volume Volume 96 (2024)
Volume Volume 95 (2024)
Volume Volume 94 (2024)
Volume Volume 93 (2023)
Volume Volume 92 (2023)
Volume Volume 91 (2023)
Volume Volume 90 (2023)
Volume Volume 89 (2022)
Volume Volume 88 (2022)
Volume Volume 87 (2022)
Volume Volume 86 (2022)
Volume Volume 85 (2021)
Volume Volume 84 (2021)
Volume Volume 83 (2021)
Volume Volume 82 (2021)
Volume Volume 81 (2020)
Volume Volume 80 (2020)
Volume Volume 79 (2020)
Volume Volume 78 (2020)
Volume Volume 77 (2019)
Volume Volume 76 (2019)
Volume Volume 75 (2019)
Volume Volume 74 (2019)
Volume Volume 73 (2018)
Volume Volume 72 (2018)
Volume Volume 71 (2018)
Volume Volume 70 (2018)
Volume Volume 69 (2017)
Volume Volume 68 (2017)
Volume Volume 67 (2017)
Volume Volume 66 (2017)
Volume Volume 65 (2016)
Volume Volume 64 (2016)
Volume Volume 63 (2016)
Volume Volume 62 (2016)
Volume Volume 61 (2015)
Volume Volume 60 (2015)
Volume Volume 59 (2015)
Volume Volume 58 (2015)
Volume Volume 57 (2014)
Volume Volume 56 (2014)
Volume Volume 55 (2014)
Volume Volume 54 (2014)
Volume Volume 53 (2013)
Volume Volume 52 (2013)
Volume Volume 51 (2013)
Volume Volume 50 (2013)
Volume Volume 49 (2012)
Volume Volume 48 (2012)
Volume Volume 47 (2012)
Volume Volume 46 (2012)
Volume Volume 45 (2011)
Volume Volume 44 (2011)
Volume Volume 43 (2011)
Volume Volume 42 (2011)
Volume Volume 41 (2010)
Volume Volume 40 (2010)
Volume Volume 39 (2010)
Volume Volume 38 (2010)
Volume Volume 37 (2009)
Volume Volume 36 (2009)
Volume Volume 35 (2009)
Volume Volume 34 (2009)
Volume Volume 33 (2008)
Volume Volume 32 (2008)
Volume Volume 31 (2008)
Volume Volume 30 (2008)
Volume Volume 29 (2007)
Volume Volume 28 (2007)
Volume Volume 27 (2007)
Volume Volume 26 (2007)
Volume Volume 25 (2006)
Volume Volume 24 (2006)
Volume Volume 23 (2006)
Volume Volume 22 (2006)
Volume Volume 21 (2005)
Volume Volume 20 (2005)
Volume Volume 19 (2005)
Volume Volume 18 (2005)
Volume Volume 17 (2004)
Volume Volume 16 (2004)
Volume Volume 15 (2004)
Volume Volume 14 (2004)
Volume Volume 13 (2003)
Volume Volume 12 (2003)
Volume Volume 11 (2003)
Volume Volume 10 (2003)
Volume Volume 9 (2002)
Volume Volume 8 (2002)
Volume Volume 7 (2002)
Volume Volume 6 (2002)
Volume Volume 5 (2001)
Volume Volume 4 (2001)
Volume Volume 3 (2001)
Volume Volume 2 (2001)
Volume Volume 1 (2000)
Soliman, B., Ali, M., Toraih, E., Ahmed, M. (2018). Mitochondrial Translocase Expression Profile in Renal Cancer. The Egyptian Journal of Hospital Medicine, 70(6), 974-979. doi: 10.12816/0044346
Belal Ahmed Soliman; Mohamed Hassany Ali; Eman Ali Toraih; Mohamed Abdelhamid Hasan Ahmed. "Mitochondrial Translocase Expression Profile in Renal Cancer". The Egyptian Journal of Hospital Medicine, 70, 6, 2018, 974-979. doi: 10.12816/0044346
Soliman, B., Ali, M., Toraih, E., Ahmed, M. (2018). 'Mitochondrial Translocase Expression Profile in Renal Cancer', The Egyptian Journal of Hospital Medicine, 70(6), pp. 974-979. doi: 10.12816/0044346
Soliman, B., Ali, M., Toraih, E., Ahmed, M. Mitochondrial Translocase Expression Profile in Renal Cancer. The Egyptian Journal of Hospital Medicine, 2018; 70(6): 974-979. doi: 10.12816/0044346

Mitochondrial Translocase Expression Profile in Renal Cancer

Article 16, Volume 70, Issue 6, January 2018, Page 974-979  XML PDF (491.97 K)
Document Type: Original Article
DOI: 10.12816/0044346
View on SCiNiTO View on SCiNiTO
Authors
Belal Ahmed Soliman1; Mohamed Hassany Ali email 1; Eman Ali Toraih2; Mohamed Abdelhamid Hasan Ahmed3
1Department of Zoology, Faculty of Science, Suez Canal University
22 Department of Histology and Genetics, Faculty of Medicine, Suez Canal University
3Department of Pathology, Faculty of Medicine, Suez Canal University
Abstract
Background: mitochondrial appropriate function depends on ideal mitochondrial translocation machinery, of which translocase of outer mitochondrial membrane (TOMM) have a vital role in normal functioning cell. Any disturbance in the translocation machinery leads to either tumorigenesis or apoptosis.
Aim of the work: This study aimed to investigate the expression of TOMM34 in renal cell carcinoma (RCC). TOMM34 expression was assessed in 42 samples of RCC patients using immunohistochemistry technique.
Results: immunohistochemical staining revealed significant accumulation of TOMM34 protein in RCC cases compared to their corresponding non-cancerous renal tissues. TOMM34 protein expression was significantly associated with age and gender categories in contrast to the other clinicopathological features.
Conclusion: according to protein expression level this study demonstrated that TOMM34 is a marker of poor outcome in RCC.
 
Keywords
RCC; TOMM34; IHC
Statistics
Article View: 121
PDF Download: 263