Moustafa, M., Samy, M., Omar, M. (2019). Assessment of Heart Rate Variability in Young Patients with Primary Hypertension. The Egyptian Journal of Hospital Medicine, 74(2), 226-236. doi: 10.21608/ejhm.2019.22839
Mansour M. Moustafa; Mohamed Samy; Mohamed Omar. "Assessment of Heart Rate Variability in Young Patients with Primary Hypertension". The Egyptian Journal of Hospital Medicine, 74, 2, 2019, 226-236. doi: 10.21608/ejhm.2019.22839
Moustafa, M., Samy, M., Omar, M. (2019). 'Assessment of Heart Rate Variability in Young Patients with Primary Hypertension', The Egyptian Journal of Hospital Medicine, 74(2), pp. 226-236. doi: 10.21608/ejhm.2019.22839
Moustafa, M., Samy, M., Omar, M. Assessment of Heart Rate Variability in Young Patients with Primary Hypertension. The Egyptian Journal of Hospital Medicine, 2019; 74(2): 226-236. doi: 10.21608/ejhm.2019.22839
Assessment of Heart Rate Variability in Young Patients with Primary Hypertension
Cardiology Department, Faculty of Medicine, Al-Azhar University (Cairo)
Abstract
Objective: this study aimed to determine the association between HRV and hypertension young adult patients, the effect of antihypertensive medications on HRV parameters was also studied. Subjects and Methods: 70 subjects under age of 40 years were classified into two groups: A- Patients’ group, It included 50 subjected they were classified according to type of antihypertensive medications into 3 subgroups; 1): 20 patients on ACE-I, (2): 15 patients on BB, 3): 15 patients on CCB. B)- Control group included 20 healthy subjects. Pulse rate, BP, ECG, and 24h Holter monitor were used to measure heart rate variability (HRV). Results: high statistical significant difference was found between patients and control according to SDNN rMSSD, pNN50 and LF/HF ratio ( P < 0.001). HRV parameters showed improvement in patient treated by BB and ACE-I, whereas no improvement was seen in patients treated by CCB. Conclusion: disturbed cardiac autonomic function was found in young hypertensive patients, treating such patients with either BB or ACE-I was associated with improvement of such autonomic imbalance.