EL- Sayed, S., Osman, H. (2007). Electron Microscopic study of Desmosomes and Tonofilaments in Lichen Planus. The Egyptian Journal of Hospital Medicine, 28(1), 363-370. doi: 10.21608/ejhm.2007.17668
Sawsan Khalifa EL- Sayed; Hossam El- Dein Hussin Osman. "Electron Microscopic study of Desmosomes and Tonofilaments in Lichen Planus". The Egyptian Journal of Hospital Medicine, 28, 1, 2007, 363-370. doi: 10.21608/ejhm.2007.17668
EL- Sayed, S., Osman, H. (2007). 'Electron Microscopic study of Desmosomes and Tonofilaments in Lichen Planus', The Egyptian Journal of Hospital Medicine, 28(1), pp. 363-370. doi: 10.21608/ejhm.2007.17668
EL- Sayed, S., Osman, H. Electron Microscopic study of Desmosomes and Tonofilaments in Lichen Planus. The Egyptian Journal of Hospital Medicine, 2007; 28(1): 363-370. doi: 10.21608/ejhm.2007.17668
Electron Microscopic study of Desmosomes and Tonofilaments in Lichen Planus
1Department of Dermatology and Venereology, Al- Azhar University for Girl, Cairo
2Anatomy Department, Al- Azhar University for Boys, Cairo
Abstract
Introduction: Lichen planus (L.P) is an idiopathic inflammatory disease of the skin and mucous membrane. Desmosomes are responsible for the adhesion of keratinocytes. Tonofilaments are one of the major cytoskeleton structure in mammalian epidermis. Patients and Methods: Six patients complained from Lichen planus are included in this study for the study of ultrastructure of both desmosomes & tonofilaments . Results: revealed an increase in the size and numbers of both of them which can be explained as a one of the defensive mechanism of the cells against frequent rubbing which is accompanied L.P. which is considered as a resistance mechanism of keratinocytes.