AL-Shinnawy, M. (2008). Effects Of Orally Fed Diazinon On Some Biochemical Parameters Of Male Albino Rats. The Egyptian Journal of Hospital Medicine, 33(1), 559-568. doi: 10.21608/ejhm.2008.17618
Mohammed Salah Ab.Ab. AL-Shinnawy. "Effects Of Orally Fed Diazinon On Some Biochemical Parameters Of Male Albino Rats". The Egyptian Journal of Hospital Medicine, 33, 1, 2008, 559-568. doi: 10.21608/ejhm.2008.17618
AL-Shinnawy, M. (2008). 'Effects Of Orally Fed Diazinon On Some Biochemical Parameters Of Male Albino Rats', The Egyptian Journal of Hospital Medicine, 33(1), pp. 559-568. doi: 10.21608/ejhm.2008.17618
AL-Shinnawy, M. Effects Of Orally Fed Diazinon On Some Biochemical Parameters Of Male Albino Rats. The Egyptian Journal of Hospital Medicine, 2008; 33(1): 559-568. doi: 10.21608/ejhm.2008.17618
Effects Of Orally Fed Diazinon On Some Biochemical Parameters Of Male Albino Rats
Biological and Geological Sciences Department , Faculty of Education , Ain Shams University , Cairo , Egypt .
Abstract
Background:The current investigation was carried out to study the effect of orally administration of diazinon insecticide on some biochemical blood indices on male albino rats. Material and methods: The organophosphorus insecticide , diazinon was orally administrated at a dose (100mg/kg body weight=1/3LD50) , daily for 10 days (short –term) and 20 days (long –term) to adult male albino rats . Results: The results revealed the following:
1- Diazinon led to an increase in rat blood serum glucose& T3 (short and long –term); AST,ALT, and T4 (long-term).
2- Diazinon reduced the serum content of total cholesterol and protein in short–term treated rats.
3- Treatment of rats with diazinon did not alter activity of AST, ALT and T4 level at short –term period .In addition ; ALP serum levels were not altered in both short and long –term treated rats .