@article { author = {Refaat, Maged M. and Elnour, Nermine Abd and Shaheen, Rasha Y. and El-Gaaly, Sonya A.}, title = {Study for Assessing Prevalence and Phenotypes of Local Allergic Rhinitis}, journal = {The Egyptian Journal of Hospital Medicine}, volume = {60}, number = {1}, pages = {258-270}, year = {2015}, publisher = {Pan Arab League of Continuous Medical Education}, issn = {1687-2002}, eissn = {2090-7125}, doi = {10.12816/0013785}, abstract = {Background: Rhinitis is a global health problem that affects 20-40% of the population in developed countries and whose incidence is rising. Rising is characterized by one or more of the following symptoms: nasal congestion, rhinorrhea, sneezing and itching. It can be induced by different mechanisms and involves several etiological agents. Noninfectious rhinitis has traditionally been classified as allergic rhinitis (AR) and nonallergic rhinitis (NAR). Objective:  To evaluate the prevalence and phenotypes of local allergic rhinitis in patients with clinical manifestations of AR without evidence of systemic IgE sensitization.  Methods: This cross sectional, case-control, and nonrandomized study was  conducted on 120 patients with clinical manifestations suggestive of allergic rhinitis (selected from the allergy outpatient clinic at Ain Shams university hospitals and 20 healthy controls.  Results:  Local allergic rhinitis was diagnosed in 80% of females and 20% of males. While the patients with systemic allergic rhinitis reached 37.5% for males, and 62.5% were females. Regarding the persistence of symptoms in local allergic rhinitis it reached 88% in comparison to 67.5% in systemic allergic rhinitis. The symptoms were intermittent in 12 % of cases with local allergic rhinitis in comparison to 32.5% in systemic allergic rhinitis.  The severe symptoms outweighed the mild symptoms by nearly 50%. The skin prick test reached 80% positive in cases of LAR. Those with normal levels of total IgE  level, the nasal provocation test was positive in 12.5% of cases and 7.5% negative.    }, keywords = {Local allergic rhinitis is a prevalent entity in patient evaluated with rhinitis}, url = {https://ejhm.journals.ekb.eg/article_15393.html}, eprint = {https://ejhm.journals.ekb.eg/article_15393_3925deffc58db34de9bdbe0173966575.pdf} } @article { author = {Helal, Eman G. E. and El sayed, Rasha A. A. and Abu-Taleb, Hoda M.}, title = {Studies on the Use of Aloe vera Extract as a Contraceptive in Female Rats}, journal = {The Egyptian Journal of Hospital Medicine}, volume = {60}, number = {1}, pages = {271-281}, year = {2015}, publisher = {Pan Arab League of Continuous Medical Education}, issn = {1687-2002}, eissn = {2090-7125}, doi = {10.12816/0013786}, abstract = {Background: The study on the natural herbal contraception has become one of the main interests of modern contraceptive studies. Herbs have been used by women since the beginning of time in an attempt to control their fertility. The development of new fertility regulating drugs derived from medicinal plants is an attractive proposition, Aloe Vera is a durable plant belonging to Sousanian family. Aim of the work: This work was assessed to evaluate the probable contraceptive effect of the aqueous extract of Aloe vera plant and its effect on the some vital organs in the female albino rats. Materials and Methods: This study was performed on twenty female albino rats with an average 120-140g body weight. The animals were divided into two groups (5 /cage); Group I (Control untreated group) and Group II (Aloe vera group that supplied orally with 7 mg/kg body wt/day of the plant extract for 30 ± 2 days).Results A prolonged proestrus and estrus phases of the estrous cycle were observed in the Aloe  vera group .The mean serum level of estrogen (estradiol) was significantly increased in the Aloe  vera group as compared to the control group (P<0.01) while non significant difference was found for serum level of progesterone and the tumor markers, CA15-3 and CA-125.The results also showed a marked decline (p<0.01) in levels of the serum calcium, creatinine, urea, total proteins, albumin, globulin and ratio of TC/HDL accompanied with a marked elevation (p<0.01) in the serum phosphorus, total lipid, TC, TG, HDL and LDL levels in the Aloe  vera group in comparison with those of control group. However, levels of uric acid, AST, ALT, GGT, VLDL and ratios of LDL/HDL (risk factors) and A/G were approximately as that of the control group. Conclusion: It could be concluded that Aloe vera can be used as a contraceptive drug that can increase the estrogen level due to its phytoestrogen components such as beta sitosterol and without deleterious effects on the other vital organ ( liver and kidney), however it's use is to be restricted with women suffering from low ca++level as well as osteoporosis.    }, keywords = {Aloe vera,fertility,contraceptive,tumor markers,Kidney function,liver function}, url = {https://ejhm.journals.ekb.eg/article_15394.html}, eprint = {https://ejhm.journals.ekb.eg/article_15394_baf76a0562718f0066a2a30d67d2acd2.pdf} } @article { author = {Abdelhady, Ayman S. and Howeedy, Azza A. and Abdelsalam, Esraa B.}, title = {Features of High Risk Pregnancy Among Women Attending a District Hospital in Greater Cairo. A Case Control Study}, journal = {The Egyptian Journal of Hospital Medicine}, volume = {60}, number = {1}, pages = {282-290}, year = {2015}, publisher = {Pan Arab League of Continuous Medical Education}, issn = {1687-2002}, eissn = {2090-7125}, doi = {10.12816/0013787}, abstract = {Background: A high-risk pregnancy (HRP) refers to any medical condition or pathology that puts the mother, fetus, or neonate at increased risk for morbidity or mortality during pregnancy or childbirth. Objectives: The current study aimed to detect main features of high risk pregnancy among women attending antenatal care clinics at a district hospital in Greater Cairo to achieve finally safe motherhood and better outcome of the pregnancy. Methods: A case control study was used where pregnant women attending antenatal care at gynecological outpatient clinics of (Abol-Monagga district hospital (MOH), Shobra El-Khema district, Greater Cairo) were investigated three days weekly during January and February 2015 for being at high risk pregnancy using a modified form of Morrison and Olsen scoring tool to form the case group (141women), while women whose pregnancy was proved to be normal or at low risk were included as a control group (181 women). Results revealed that the main current associated morbidities of the high risk pregnancy women included anemia in (17%),gestational DM (14%),pregnancy induced hypertension (13%)and gynecological disorders in(27%).The most prominent features which were significantly related to development of HRP among studied women included obesity (31.2%), history of previous pregnancy associated morbidities  (24.8%), previous delivery with CS (24.1%), multigravidae (32.6 %), multiparity (19.9 %), recurrent abortions (14.2 %)  and complicated previous pregnancy outcome in (31.9%), while insignificantly detected factors included un-optimal maternal reproductive age (<18 & >35 years), working during pregnancy, illiteracy, (+ve) husband consanguinity, non practicing regular physical activities during pregnancy, (+ve) past history of infertility and family history of morbidities. Conclusion and recommendations: Comparing (HRP) women with normal and low risk group revealed a higher prevalence of current morbidities such as anemia, DM and HTN among (HRP) women in addition to other risk factors such as obesity, multigravidae, multiparity, past history of delivery with CS, recurrent abortions and complicated previous pregnancy outcome. The study recommended proper screening techniques to be used for all pregnant women attending antenatal care clinics to pick up the factors that qualify the pregnant women to be at high risk. Preconception assessment and counseling are strongly encouraged and should include the provision of specific information concerning the risk factors which predispose to risky pregnancy.  }, keywords = {High risk pregnancy,maternal morbidity,antenatal care}, url = {https://ejhm.journals.ekb.eg/article_15395.html}, eprint = {https://ejhm.journals.ekb.eg/article_15395_2550d514d42859c2c0ab7e6d4111cf63.pdf} } @article { author = {AbdElhamid, Hamdy and Settin, Ahmed and El-baz, Risk and Elnaby, Sobhy Hassab and Roshdy, Sameh and Noaman, Ahmed}, title = {Genetic Polymorphisms of Vascular Endothelial Growth Factor (VEGF) in Egyptian Women with Breast Cancer}, journal = {The Egyptian Journal of Hospital Medicine}, volume = {60}, number = {1}, pages = {291-302}, year = {2015}, publisher = {Pan Arab League of Continuous Medical Education}, issn = {1687-2002}, eissn = {2090-7125}, doi = {10.12816/0013788}, abstract = {Background:Vascular endothelial growth factor (VEGF) was considered to have an association with breast cancer because it regulates endothelial cell proliferation, migration and differentiation. Subjects and methods:  One hundred and fifty two women with breast cancer were compared to 100 healthy control Egyptian women recruited from the same locality.  VEGF gene polymorphisms were assessed using the PCR-RFLP analysis of DNA samples obtained from peripheral blood.SNP scanning was performed using MnII , BsmfI , CviAII , BsmfI , MnII restriction enzymes for VEGF1154 G/A, 634 G/C, 405 C/G, 936 C/T, 1612 G/A polymorphisms, respectively. Results : Breast cancer among Egyptian women was strongly associated with the  mutations related to VEGF gene polymorphism as follows: VEGF 1154 G allele frequency was significantly higher than the A allele (P = 0.0007,O.R =2.4) , VEGF 634 C allele frequency was significantly higher than the G allele (P = 0.012, O.R =0.62),VEGF 405 C Allele frequency was significantly higher than G Allele (P = 0.009, O.R =1.67), VEGF 936 C Allele frequency was significantly higher than the T Allele (P = 0.0057, O.R =1.72), VEGF 1612 G Allele frequency was significantly higher than A allele (P = 0.0148, O.R =1.62). For VEGF 1154 GA: AA vs. GA+GG (Recessive) P = 0.10, O.R = 6.23, C.I (1.0-38.9), GA vs. AA+GG (over dominant) P= 0.01*, O.R = 2.13, C.I (1.2-3.8),AA+GA vs. GG (dominant) P= 0.0015*, O.R = 2.57, C.I (1.5-4.5). For VEGF 634 GC : CC vs. GC+GG (Recessive) P= 0.1852, O.R = 0.64, C.I (0.4-1.2), GC vs. CC+GG (over dominant) P= 0.2669 , O.R = 0.71, C.I (0.4-1.2), CC+GC vs. GG (dominant) P = 0.0002**, O.R=0.05, C.I (0.0-0.2).For VEGF 405 CG : GG vs. CG+CC (Recessive) P= 0.0013*, O.R = NA,C.I =NA, CG vs. GG+CC (over dominant) P= 0.877, O.R = 1.08, (0.6-1.9), GG+CG vs. CC (dominant) P = 0.0323*, O.R=1.93,C.I (1.1-3.4).For VEGF 936 CT : TT vs. CT+CC (Recessive) P = 0.1833, O.R = 1.63, C.I (0.9-3.1),  CT vs. TT+CC (over dominant) P = 0.1379, O.R = 1.55, C.I (0.9-2.6), TT+CT vs. CC(dominant) P = 0.0075**, O.R=2.08, C.I (1.2-3.5). For VEGF 1612 GA: AA vs. GA+GG (Recessive) P = 0.0000**, O.R = NA, C.I = NA, GA vs. AA+GG (over dominant) P= 0.0002**, O.R = 0.36, C.I (0.6-0.2), AA+GA vs. GG (dominant) P = 0.9541, O.R = 0.95, C.I (1.6-0.6).    }, keywords = {Polymorphisms,breast cancer,VEGF}, url = {https://ejhm.journals.ekb.eg/article_15397.html}, eprint = {https://ejhm.journals.ekb.eg/article_15397_a05fb0c7be0cb5866b33e58a563e599a.pdf} } @article { author = {M.S, Gabri and Moustafa, Maiada and Mohamed, Nehad and Kandil, Asmaa M.}, title = {Effect of Clarithromycin Administration during Late Gestational Period on The Pregnant Albino Rats and Their Fetuses}, journal = {The Egyptian Journal of Hospital Medicine}, volume = {60}, number = {1}, pages = {303-313}, year = {2015}, publisher = {Pan Arab League of Continuous Medical Education}, issn = {1687-2002}, eissn = {2090-7125}, doi = {10.12816/0013789}, abstract = {Clarithromycin, a new macrolide antibiotic, is effective in the management of a wide range of clinical problems including outpatient treatment of community-acquired pneumonia, shortening the course of peptic ulcer disease associated with Helicobacter pylori infection and curing previously resistant respiratory infections in immune-compromised patients. The present study is planned to study the effect of clarithromycin on the pregnant female rats and their fetuses during the last gestational period stage. This study includes the effect of clarithromycin on therate of abortion, malformation of fetuses, skeletal, histological changes and DNA fragmentation of liver cells of pregnant rats and their fetuses. In the present study two groups of pregnant animals were used. The first group received distilled water from 15th to 19th days of gestation and used as control and sacrificed at 20th day of gestation. The other group is orally administered with 45mg/kgclarithromycin from 15th to 19th days and sacrifices at 20th day of gestation (the therapeutic dose). The obtained results showed a significant decrease in maternal body weight gain and increase in the rate of abortion, resorption and growth retardation of fetuses.Fetuses of the treated group showed severe lack of ossification on the skull bones, phalanges and sternum bone as well as shortness in the ulna and radius bones. Histological studies of pregnant rats revealed congestion and dilatation of the central vein of the liver lobules and fatty degeneration of the hepatocytes with severe DNA fragmentation.In 20 day-fetuses, there were a marked increase of necrotic hepatocytes associated with increased average of megakaryocytes and periportal leukocytic infiltration.  }, keywords = {Macrolides,clarithromycin,fetogenesis,Teratology,skeletal malformation,rat and liver histopathology,DNA fragmentation}, url = {https://ejhm.journals.ekb.eg/article_15399.html}, eprint = {https://ejhm.journals.ekb.eg/article_15399_5bbbb16161ef007413b0b4649278a080.pdf} } @article { author = {Shendy, Shendy Mohammed and El-Talkawy, Mohamed Darwish and Saleem, Abdel Aziz Ali and Safwat, Wael and Adel, Mona and El-Khalik, Ashraf Abd and Abu Taleb, Hoda}, title = {Relation between Non-Alcoholic Fatty Liver Disease and Epicardial Fat in Metabolic Syndrome}, journal = {The Egyptian Journal of Hospital Medicine}, volume = {60}, number = {1}, pages = {314-323}, year = {2015}, publisher = {Pan Arab League of Continuous Medical Education}, issn = {1687-2002}, eissn = {2090-7125}, doi = {10.12816/0013790}, abstract = {Background:Non-alcoholic fatty liver disease (NAFLD) is becoming recognized as a component of the metabolic syndrome and insulin resistance. There has been recent interest in the association between epicardial fat and atherosclerotic disease with increased risk of cardiovascular mortality and morbidity. Aim of the work: In this study we investigated the relationship between the metabolic syndrome with liver involvement and epicardial fat. Patients and methods: 85 patients who had the criteria of metabolic syndrome are subjected to thorough clinical evaluation. Abdominal circumference, body mass indexand waist/hip ratio were recorded for all patients. Laboratory investigations including urine, complete blood picture, fasting and postprandial blood glucose, uric acid, blood urea and creatinine,C-reactive protein (CRP) , lipid profile, liver enzymes and bilirubin were done to all patients. Ultrasonography was used to grade fatty liver and measure the thickness of epicardial fat. Results: Patients with high ALT levels have significantly higher (p<0.01) AST, fasting blood glucose (FBG), uric acid, triglyceride (TG) level, more epicardial fat and waist circumference (p<0.05) compared to those with normal levels. Patients with high grade of fatty liver have significantly higher total cholesterol, TG, FBG, AST, ALT, uric acid levels, more epicardial fat and waist circumference (p<0.01) compared to those with mild and moderate. ALT, FBG and TG are significantly higher in patients with detectable epicardial fat than those without (p<0.01). There were significant direct correlations between epicardial fat thickness with FBG (r= 0.324; p<0.01), TG (r= 0.217; p<0.05), AST (r= 0.493; p<0.01), ALT (r= 0.561; p<0.01), and grade of fatty liver (r= 0.479; p<0.01). Also there were significant direct correlations between FBG with waist circumference (r= 0.422; p = 0.01), TG level (r = 0.370; p<0.01), HDL-C (r = 0.284; p<0.05) and grade of fatty liver (r = 0.533; p = 0.01).  There were significant direct correlations between grade of fatty liver with waist circumference (r= 0.264; p<0.05), TG (r= 0.407; p<0.01), uric acid (r= 0.288; p<0.05), and AST levels (r= 0.642 p<0.01). CRP was found correlated only with liver enzymes (r = 0.481;p<0.05). Simple logistic regression analysis revealed that epicardial fat thickness (mm) showed a trend in patients with NAFLD and metabolic syndrome. Conclusion: Echocardiographic assessment of epicardial adipose tissue, abdominal ultrasound assessment of NAFLD and transaminase level might serve as a reliable marker of visceral adiposity and more severe degree of metabolic syndrome.  }, keywords = {Non-alcoholic fatty liver disease (NAFLD),Metabolic syndrome,Epicardial fat}, url = {https://ejhm.journals.ekb.eg/article_15400.html}, eprint = {https://ejhm.journals.ekb.eg/article_15400_93ee54e295d5205da84fc5d0a89894a0.pdf} } @article { author = {Farid, Saadia and Rashed, Laila and Ahmed, Amal and Sweilam, Samya}, title = {Tumor Necrosis Factor-Alpha (TNF-α) Gene Expression in Chronic Hepatitis B Virus Infection}, journal = {The Egyptian Journal of Hospital Medicine}, volume = {60}, number = {1}, pages = {324-335}, year = {2015}, publisher = {Pan Arab League of Continuous Medical Education}, issn = {1687-2002}, eissn = {2090-7125}, doi = {10.12816/0013791}, abstract = {Background: Tumor necrosis-alpha (TNF-α) is produced by macrophages, neutrophils, T-cells and NK-cells after stimulation. In turn, TNF-α can stimulate secretion, increase the expression of adhesion molecules as well as active neutrophils. Hence, it fulfills the role as a principal mediator of cellular immune response and inflammation, and may play an important role in non-cytopathic and cytolytic clearance of hepatitis B virus (HBV). The clearance of HBV is a complex process which may be influenced by many factors including polymorphisms in the tumor necrosis (TNF-) gene promoter. Aim of the work: The study aimed to determine the TNF-α as a gene expressed in chronic hepatitis B virus infection and its role in outcome of the virus. Patients and methods:  Ninety four patients with chronic  HBV infection, their age between 19 and 59 years, selected from the National Hepatology and Tropical Medicine Research Institute were included in this study, during treatment and twenty healthy individuals were included to serve as controls. All the patients and controls were subjected to the following; history, clinical examination, abdominal ultrasonography and collection of blood samples for routine laboratory investigation, and serological assay for HBsAg, HBsAb, HBeAg, HBeAb, HBV DNA (quantitative), and TNF-α promoter polymorphisms in two sites 238 and 308. Results: The prevalence of the variant at position -308 GA was similar in all investigated groups (patients and controls).An association was found between the TNF-α promoter polymorphism at position -238 and the development of chronic HBV infection with sensitivity of 93% and specificity of 75%. Conclusion: TNF-α-308 GA was significantly associated with clearance, showing protective antibody and persistent HBV infection. The promoter variant of TNF-α at position 238 GA, GG appears to be linked to defective viral clearance, controls had higher TNF-α-238 GG,GA, AA as compared to cases with significant difference. Recommendations: The variation in the genes governing the levels of constitutive and inducible TNF-α might be an important factor, which might explain the variable outcome of HBV infection.  }, keywords = {Hepatitis B virus (HBV),Tumor necrosis factor ,Polymorphism,and “SNP” single nuclueotide polymorphism at 238,and 308}, url = {https://ejhm.journals.ekb.eg/article_15402.html}, eprint = {https://ejhm.journals.ekb.eg/article_15402_568983b861a74c1f654f7c22ccd58e3c.pdf} } @article { author = {Hassan, Hanaa A. and EL-Kholy, Wafaa M. and Galal, Nadine A.}, title = {Comparative Protective Effect of Moringa and Dandelion Extracts Against Hepatic Disorders and Oxidative Stress Associated with Prolonged Use of BrufenDrug in Rats}, journal = {The Egyptian Journal of Hospital Medicine}, volume = {60}, number = {1}, pages = {336-346}, year = {2015}, publisher = {Pan Arab League of Continuous Medical Education}, issn = {1687-2002}, eissn = {2090-7125}, doi = {10.12816/0013792}, abstract = {Bachground: The nonsteroidal anti-inflammatory drugs (NSAIDs) are the most frequently used medications worldwide for the treatment of a variety of common chronic and acute inflammatory conditions. The association between NSAIDs and liver disease is poorly documented. Aim: the current study was carried out to investigate the hepatic disorders associated with prolonged use of Brufen drug and evaluate the role of both moringa and dandelion extracts as hepatoprotective agents against these disorders. Methods: rats were divided into six groups (six rats/ each) as follow: group 1: rats did not receive any treatment and  served as control;      group 2 : rats orally administrated moringa extract (300mg/kg b.wt) daily for 12 weeks; group 3: rats orally administrated dandelion extract (300mg/kg b.wt) daily for 12 weeks ; group 4: rats orally administrated Brufen (18mg/kg b.wt) daily for 12 weeks;.group5: rats orally administrated moringa extract (300mg/kg b.wt) daily for one week alone then concomitant with Brufen (18mg/kg b.wt) for 11 weeks ;group 6: rats orally administrated dandelion extract (300mg/kg b.wt) daily for one week alone then concomitant with Brufen (18mg/kg b.wt) for 11 weeks.Results: the present results showed that the administration of Brufen led to significant increases in the levels of TL, TC, TG, LDL-C, ALT, AST, ALP, GGT, MDA and XO. While significant decreases in HDL-C, TP, ALP, GSH, TAC, SOD, CAT and GSH-Px, were recorded in Brufen treated rats group. On the other hand, the administration moringa or dandelion extracts succeeded to alleviate these abnormalities resulted from Brufen drug as indicated by the clear amelioration of occurred hepatic metabolic disorders, oxidative stress and histopathological changes in addition to improvement of the antioxidant status. Conclusion: it could be concluded that moringa or dandelion extracts have a remarkable role in management the hepatic disorders and oxidative stress associated with prolonged use of Brufen. Additionally it was recorded that moringa extract was more beneficial than dandelion extract in alleviating the occurred adverse effects of Brufen.  }, keywords = {Moringa,Dandelion,Hepatic disorders,Brufen drug}, url = {https://ejhm.journals.ekb.eg/article_15403.html}, eprint = {https://ejhm.journals.ekb.eg/article_15403_b3b753f270e5bac0e404c37a87925db8.pdf} } @article { author = {Younes, Mahmoud I. and Basuony, Ali E.}, title = {Age Structure of a Red Fox (Vulpes vulpes) Sample from Egypt}, journal = {The Egyptian Journal of Hospital Medicine}, volume = {60}, number = {1}, pages = {347-353}, year = {2015}, publisher = {Pan Arab League of Continuous Medical Education}, issn = {1687-2002}, eissn = {2090-7125}, doi = {10.12816/0013793}, abstract = {Background:the Red Fox Vulpes vulpes is the most common and wide spread wild carnivore in Egypt. Materials and methods:we examine a museum sample of 179 specimens from different parts of Egypt to determine age structure using dentine layers counting method. Specimens were grouped into three population groups according to their geographical region of origin. Results:the average age of foxes in the sample was 1.46 years and ranging from 1 to 7 years of age. Differences in age structure of populations from the three geographical regions and differences between sexes are presented and discussed.  }, keywords = {red fox,Age structure,Dentine layers,Age classes}, url = {https://ejhm.journals.ekb.eg/article_15405.html}, eprint = {https://ejhm.journals.ekb.eg/article_15405_4c192ace7ec251e1d6247a4334f0d322.pdf} } @article { author = {Hosny, Hesham M. and Wahab, Adel M. Abdul and Abdallah, Mona El Sayed Ali H Jihan and Mahmoud, Doaa Ali}, title = {Is Lasik an Effective Treatment Modality for Hyperopia or Hyperopic Astigmatism?}, journal = {The Egyptian Journal of Hospital Medicine}, volume = {60}, number = {1}, pages = {354-362}, year = {2015}, publisher = {Pan Arab League of Continuous Medical Education}, issn = {1687-2002}, eissn = {2090-7125}, doi = {10.12816/0013794}, abstract = {Purpose: To assess the efficacy, safety and stability of LASIK surgery for treatment of low to moderate degree hyperopia and hyperopic astigmatism. Patients and methods: The study included 34 eyes in 17 patients (7 males, and 10 females) with bilateral low to moderate degree hyperopia or hyperopic astigmatism. Their mean age + SD was 26.7 + 4.1 years. Range of hyperopia was between +1.75 to +5.50 D, astigmatic errors range was 0.00 to -1.50 D while the spherical equivalent refraction ranged from +1.4 to + 4.8 D. Patients included in this study had a stable refraction for at least one year. All patients underwent bilateral LASIK surgery in the same session in Dr Soliman Faqeeh Hospital (DSFH) and the Eye Subspecialty Center (ESC) using the ALLEGRETTO EYE - Q Excimer Laser machine. Results:UCVA after one year was 20/20 or better in 30 eyes (88.2%), 20/30 or better in 32 eyes (94.1%) and 20/40 or better in 34 eyes (100%), while BCVA was 20/20 or better in 33 eyes (97.1%) and 20/40 or better in 34 eyes (100%). There was no decrease in UCVA after LASIK surgery. One eye (2.9%) showed 2 lines drop in BCVA after LASIK surgery due to broad wrinkles of the flap. The flap was lifted after one day; trial to flatten the wrinkles showed incomplete resolution. One eye (2.9%) showed diffuse lamellar keratitis (DLK) at one week after LASIK surgery. There was regression in the manifest spherical equivalent refraction one year after LASIK surgery as compared with that at one month, but the difference was statistically insignificant (P=O.46). The mean score of patient satisfaction was 9.4 at one year postoperatively. Conclusion: LASIK surgery is a safe, predictable, stable and effective for treatment of mild to moderate degree hyperopia and hyperopic astigmatism. No significant regression in UCVA, BCVA or manifest refraction was reported up to 12 months follow up.    }, keywords = {LASIK,Ablation,Hyperopia,Astigmatism,pentacam}, url = {https://ejhm.journals.ekb.eg/article_15406.html}, eprint = {https://ejhm.journals.ekb.eg/article_15406_ff6118ab7121140d1309a23431a0698a.pdf} }